BIMI200 quiz

The transition state theory indicates that products are only formed after the reactant species...

• are lock and key

• has acquired sufficient energy to reach a transition state wherein the bond breaking or bond forming chemistry is at some stage of development.

• have an induced fit model

• Collided in an minimum spatial orientation that will progress to a chemical reaction between them.

Lock and Key Model states that.....

• To fit into an active site the substrate must have a matching or complementary shape.

• To fit into the substrate site the enzyme must have a matching or complementary shape.

• The active sites of these enzymes have shapes that are complimentary to that of the substrate only after the substrate is bound to the enzyme.

• The role of the enzyme is to lock the key substrate inside

The lock and key model is also known as

• Inhibitory recognition

• Induced recognition

• Dynamic recognition

• Static recognition

The ....................implies distortion of the enzyme as well as the substrate

• static recognition

• induced fit model

• lock and key model

• competitive inhibition

During irreversible enzyme inhibition the substances combine................... with enzymes so as to inactivate them irreversibly

• ionically

• covalently

• Non-covalently

• allosterically

An example of an irreversible inhibitor is.........

• Succinate

• Cyanide

• Serine

• Distilled water

At temperatures above 60°C enzymes are.............

• inactivated

• functioning optimally

• are functioning at increasing rate

• maintaining their native conformation

This vitamin structure has a substituted pyrimidine and a substituted thiazole joined by a methylene bridge.

• Vitamin B1

• Vitamin A

• Vitamin C1

• Vitamin C12

The deficiency of this vitamin could lead to brain damage

• Vitamin B1

• Vitamin B12

• Vitamin B6

• Vitamin B14

An example of fat-soluble vitamin is

• Biotin

• Vitamin C

• Vitamin E

• Vitamin B