Hypersensitivity Reactions

An increased (exaggerated) response of normal immune system that damages the body tissues is known as ___

• hypersensitivity

• hypersensitivity reaction

• Allergy

• All the above

Which of the following is called Delayed-type hypersensitivity reaction?

• Type II

• Type I

• Type IV

• Type III

Antigens in bee sting venom, pollens, nuts may cause ____ hypersensitivity reaction.

• Anaphylactic

• Immune-complex mediated

• antibody-mediated cytotoxic

• Delayed type

Sensitization phase in delayed type hypersensitivity reaction takes ___ time.

• 1-2 weeks

• 4-5 weeks

• 1-2 months

• 3-5 days

IFN-γ, TNF-β, IL-2 are examples of ___

• Antigens

• Cytokines

• Immunoglobulins

• Antibodies

In type I reaction, IgEs trigger mast cells to produce ___

• Antibody

• Histamine

• Allergen

• Interleukin

Which of the following is true for hypersensitivity reactions?

• The reaction during a blood transfusion is an example of a Type II hypersensitivity reaction (cytotoxic hypersensitivity).

• The reaction during a blood transfusion is an example of a Type III

• The reaction during a blood transfusion is an example of a delayed type reaction

• The reaction during a blood transfusion is an example of antigen mediated reaction

Hemolytic disease of the newborn caused by Rh incompatibility in a subsequent pregnancy can be prevented by administering antibodies against the Rh antigen to the mother. These antibodies are called ____

• Rhogam

• Rh Antigen

• Rh Factor

• RhO anti antibody

Localized Arthus reaction (reaction at site of injection) and generalized reactions such as serum sickness, rheumatoid arthritis, and systemic lupus erythematosus. These are due to ____ reaction.

• Type 1

• Type 2

• Type 3

• Type 4

____ are proteins in type II reactions that bind to foreign particles and bacteria making them more susceptible to the action of phagocytes.

• Opsonins

• Haptens

• Interleukins

• Cytokines