Henderson Hasselbalch

In the Henderson-Hasselbalch equation, what does "p" represent?

• The power of the concentration

• The negative logarithm

• The pressure of the system

• The product of the concentrations

If you know the pH and pK_a of a solution, what can you determine?

• The temperature of the solution

• The ratio of [A-] to [HA]

• The molecular weight of the solute

• The viscosity of the solution

If the pH is one unit above the pKa of an amino acid group, approximately what percentage of the amino acid exists in the deprotonated [A-] form?

• 50%

• 91%

• 99%

• 99.9%

If the pH is 2 units below the pKa of an amino acid group, approximately what percentage of the group is in the protonated [HA] form?

• 91%

• 99%

• 50%

• 99.9%

What happens to the ratio of [A-] to [HA] when the pH is equal to the pKa of the amino acid group?

• [A-]/[HA] = 10

• [A-]/[HA] = 100

• [A-]/[HA] = 1

• [A-]/[HA] = 0

What is the ratio of [A-] to [HA] if the pH is two units above the pKa of the amino acid group?

• [A-]/[HA] = 1

• [A-]/[HA] = 10

• [A-]/[HA] = 100

• [A-]/[HA] = 1000

At a pH three units above the pKa, what is the approximate percentage of the amino acid in the [A-] form?

• 50%

• 91%

• 99%

• 99.9%

At pH 7, the -COOH group on an alpha carbon is predominantly in what state?

• Protonated (-COOH) form

• Deprotonated (-COO-) form

• Neutral

• Protonated (-NH3+) form

Which of the following represents the dominant form of lysine at pH 10.0? Carboxyl Group = 2.2 Backbone = 9.1 SideChain = 10.5 Normal pH is 7.0

• A

• B

• C

• D

In the Henderson-Hasselbalch equation, what does the term 'pKa' represent?

• The concentration of the acid

• The negative logarithm of the acid dissociation constant

• The pressure of the acid

• The temperature of the solution