Antitubercular drugs

The aim/s for tubercular treatment is/are

• to prevent recurrent.

• to promote drug resistance.

• to prevent disease transmission.

• to eradicate the infection.

Peculiar features of mycobacterium tuberculosis includes the presence of ______ pumps.

One of the reasons Mycobacterium infections are difficult to treat is

• it contains thick lipid layer of its cell wall.

• the presence of influx pumps.

• its size.

• none of the above.

Rifampicin inhibits .......subunit of RNA polymerase.

• alpha

• beta

• delta

• gamma

Rifampicin is a cytochrome

• inhibitor.

• inducer.

Isoniazid interferes with mycobacterial mycolic acid synthesis.

• TRUE

• FALSE

Slow acetylator individuals will have lesser amount of isoniazid toxic metabolites.

• TRUE

• FALSE

Isoniazid -------- metabolism of warfarin.

• increases

• reduces

Pyrazinamide increase urate excretion.

• TRUE

• FALSE

The use of ethambutol spares a patient for a periodic visual assessment.

• TRUE

• FALSE