Methylation and Acetylation

What can DNA methylation cause in terms of gene activity?

• Short-term activation of genes.

• Long-term activation of genes.

• Long-term inactivation of genes.

• Immediate inactivation of genes.

Tags

NGSS.HS-LS3-2

What is the effect of DNA methylation on the transcription of certain DNA bases?

• It increases transcription.

• It has no effect on transcription.

• It reduces transcription.

• It completely stops transcription.

What is the effect of the addition of methyl groups (methylation) to chromatin?

• It promotes the initiation of transcription

• It opens up the chromatin structure

• It condenses chromatin and reduces transcription

• It attaches acetyl groups to amino acids in histone tails

What is the result of histone acetylation on chromatin structure?

• It condenses chromatin and reduces transcription

• It has no effect on chromatin structure

• It opens up the chromatin structure, promoting the initiation of transcription

• It removes acetyl groups from the histone tails

What is the primary effect of DNA methylation on gene expression?

• It activates gene expression.

• It silences gene expression.

• It has no effect on gene expression.

• It enhances gene expression.

Tags

NGSS.HS-LS3-2

Which enzyme is responsible for adding methyl groups to DNA?

• DNA polymerase

• DNA ligase

• DNA methyltransferase

• DNA helicase

How does histone acetylation affect chromatin structure?

• It condenses chromatin, reducing transcription.

• It opens up chromatin, promoting transcription.

• It has no effect on chromatin structure.

• It removes methyl groups from DNA.

What is the role of acetyl groups in histone modification?

• They condense chromatin.

• They promote chromatin relaxation.

• They methylate DNA.

• They degrade histones.

Which of the following is a consequence of DNA methylation in cancer cells?

• Increased tumor suppressor gene expression

• Decreased oncogene expression

• Silencing of tumor suppressor genes

• Activation of DNA repair genes

What is the effect of histone deacetylation on gene expression?

• It activates gene expression.

• It silences gene expression.

• It has no effect on gene expression.

• It enhances gene expression.