Cell Cycle Mitosis and Cancer

In general, the purpose of a checkpoint in the cell cycle is:

• To allow the cell to rest

• To check for any errors

• To signal cell replication

• To signal DNA replication

These move the chromosomes during mitosis

• spindle fibers

• deep furrows

• centromeres

• centrioles

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the uncontrolled division of cells that results in malignant growth 

• tissues

• cancer

• mitosis

• anaphase

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In this phase of the cell cycle, the cell grows bigger.

• G1

• S

• G2

• mitosis/cytokinesis

An abnormal mass of cancer cells is called a...

• benign

• lesion

• tumor

• G0 phase

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Normal cells have a contact inhibition feedback mechanism that prevents the cells from replicating when other cells are touched. A diagram of cells with contact inhibition and cells without contact inhibition is shown. Which statement best describes what will happen to cells in an organism that lack contact inhibition?

• The cells will continue to grow, causing a tumor in the body.

• The cells will replicate normally, replacing body cells that die.

• The cells will replicate until the food supply for each cell is used, causing each cell to die.

• The cells will stop replicating once one layer is produced, as other body cells will crowd them out.

Answer explanation

"contact inhibition" means that when they come in contact with something, they will STOP replicating. So, if cells are able to do this "contact inhibition" , they will continuously replicate causing cancer.

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Scientists determined the total mass of DNA from a sample of animal cells. The masses of equal numbers of cells were taken during three different stages of the cell cycle. Stage I contains cells massed during G1 of the cell cycle. During the Cell Cycle Which statement best describes the cells during Stage II?

• The cells have replicated their DNA, but have not completed mitosis and cytokinesis.

• The cells have completed mitosis and cytokinesis without replicating their DNA.

• The cells have replicated their DNA and completed mitosis and cytokinesis.

• The cells have temporarily exited the cell cycle without replicating their DNA.

Answer explanation

DNA is doubled during S-Phase, which is in interphase. Therefore, if you are looking at a cell with a large amount of DNA, it has gone through S-Phase, but hasn't divided yet.

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Match the following stages of the cell cycle with their description

• Cell prepares to divide

• S-Phase

• Actual cell division

• Cytokinesis

• DNA is replicated

• Interphase

• G1 + S + G2

• Mitosis (M-Phase)

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The growth phase of the cell cycle is called

• Interphase

• Telophase

• Prophase

• Anaphase

Two identical chromatids are called...

• Daughter Chromatids

• Sister Chromatids

• Brother Chromatids

• Twin Chromatids

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