Electrophilic Aromatic Substitution

Which of the following is a step in the general mechanism for the electrophilic aromatic substitution?

• A
• B
• C
• D

Under what reaction conditions does the electrophilic chlorination of aromatic compounds usually occur?

• Cl₂, AlCl₃
• Cl₂, H₂O
• Cl₂, CCl₄
• NaCl, H₂O

What is the organic product of the following reaction?

• A
• B
• C
• D

Tags

NGSS.HS-PS1-1

NGSS.HS-PS1-2

Which of the following compounds will undergo bromination most rapidly using Br₂, FeBr₃?

• p-methylacetanilide
• bromobenzene
• acetanilide
• dibromobenzene

Tags

NGSS.HS-PS1-5

Which of the following compounds will react most rapidly when treated with CH₃CH₂Cl and AlCl₃?

• benzene
• chlorobenzene
• anisole
• toluene

Tags

NGSS.HS-PS1-5

In electrophilic aromatic substitution reactions, a -CO₂H substituent on the aromatic ring is

• a deactivator and a m-director
• a deactivator and an o,p-director
• an activator and a m-director
• ) an activator and an o,p-director

In electrophilic aromatic substitution reactions, a -NHCOCH₃ substituent on the aromatic ring is

• a deactivator and a m-director
• a deactivator and an o,p-director
• an activator and a m-director
• an activator and an o,p-director

What is the organic product of the following reaction?

• A
• B
• C
• D

Tags

NGSS.HS-PS1-1

NGSS.HS-PS1-2

⁺NO₂

• The reactive electrophile in Friedel-Crafts acylation reactions.

• The electrophile in aromatic nitration.

• Groups which activate aromatic rings towards electrophilic substitution.

• Groups which activate aromatic rings towards nucleophilic substitution.

• Source of F⁺ in fluorination reactions.

F-TEDA-BF₄

• The reactive electrophile in Friedel-Crafts acylation reactions.

• The electrophile in aromatic nitration.

• Groups which activate aromatic rings towards electrophilic substitution.

• Groups which activate aromatic rings towards nucleophilic substitution.

• Source of F⁺ in fluorination reactions.