Cell Cycle Checkpoint and Cancer

What is cancer?

• A group of diseases characterized by no cell growth

• A group of diseases caused by the failure of chromosomes to separate

• A group of diseases characterized by uncontrolled cell division

• A group of diseases caused by excessive replication of chromosomes

Tags

NGSS.HS-LS3-2

Which of the following is NOT an external factor that will promote cell growth

• An increase in growth hormone

• A decrease in growth hormone

• Death of nearby cells

• Decrease in surface area to volume ratio

Which cell cycle checkpoint verifies cell size and checks the DNA for damage?

• G1 checkpoint

• S checkpoint

• G2 checkpoint

• M checkpoint

Which cell cycle checkpoint makes sure that chromosomes are duplicated and checks for damage of the replicated DNA?

• G1 checkpoint

• S checkpoint

• G2 checkpoint

• M checkpoint

Which cell cycle checkpoint makes sure that the chromatids are correctly attached to the spindle fibers?

• G1 checkpoint

• S checkpoint

• G2 checkpoint

• M checkpoint

Tags

NGSS.HS-LS1-4

What are cyclins and cyclin dependent kinases?

• regulatory proteins

• carcinogens

• mitotic proteins

• mutagens

Tags

NGSS.HS-LS1-4

Who type of protein prevents the cells with damage form continuing through the cell cycle?

• tumor supressor

• tumor initiator

• stem cell suppressor

• stem cell initiator

Which of the following is a true statement?

• Benign tumors have cells that have broken away from the main tumor.

• Malignant tumors have cells that have broken away from the main tumor.

• Malignant tumors consist of cells that have stayed together.

• Benign tumors spread through the blood and lymph to other organs

Which of the following is not a way that genes for cell cycle regulatory proteins can be damaged?

• cell crowding

• carcinogens

• inherited mutations

• exposure to certain viruses

Which two two factors can inhibit the progression of a cell through the cell cycle?

• cell crowding and a decrease in surface area to volume ratio

• cell crowding and decrease in growth hormone