DNA Repair

Which of the following mechanisms will remove uracil and incorporate the correct base?

• Direct repair

• Base excision repair

• Mismatch repair

• Nucleotide excision repair

DNA damage caused by alkylating agents is repaired by which mechanism?

• Nucleotide excision repair

• Single stranded basic repair

• Double stranded break repair

• Mismatch repair

Difference between global genomic (GG) & transcription coupled (TC) nucleotide excision repair?

• In TC repair an staled RNA polymerase is identified

• In GG repair an staled RNA polymerase is dentified

• GG uses CSA and CSB before XPA

• TC uses CSA and CSB before XPA

What is the main enzyme that plays the major role in formation of thymine dimer?

• a) DNA glycosylase

• b) DNA photolyase

• c) DNA gyrase

• d) DNA ligase

In SOS repair system cleavage of LexA and UmuD is mediated by ___________

• a) RecB

• b) RecA

• c) RecC

• d) UvrA

In the following compounds which are involved in nucleotide excision repair?

• a) UvrA, UvrB, UvrC

• b) UvrC, UvrD

• c) Uvr C, XPA, XPD

• d) XPA, XPC, XPD, XPG

In mismatch repair mechanism which of the following protein recognizes DNA mismatches in genomic DNA?

• Mut H

• Mut S

• Mut L

• UVR A

The activity of AP endonuclease is seen in

• Base excision repair

• nucleotide excision repair

• mismatch repair

• double stranded break repair

Which of the DNA repair mechanism is known as the 'cut and patch mechanism?

• Photoreactivation

• Nucleotide excision repair

• Base excision repair

• Mismatch repair

Xenoderma pigmentosum in humans is associated with a mutation in

• photoreactivation

• Nucleotide excision repair

• Mismatch repair

• Base excision repair

Tags

NGSS.HS-LS3-2