#2 HHMI Mismatch Repair in DNA Replication Quiz

What is the primary function of DNA polymerase during DNA replication?

• To repair mutations
• To copy both strands of DNA
• To synthesize proteins
• To unwind the DNA helix

Which of the following correctly describes a potential mutation during DNA replication?

• Incorporating an A where a T should be
• Incorporating a T where a C should be
• Incorporating a C where a G should be

What role do the proteins MSH2, MSH6, MLH1, and PMS2 play in the cell?

• They synthesize new DNA strands
• They repair mutations in DNA
• They unwind the DNA double helix
• They initiate DNA replication

What is the function of EXO1 in the DNA repair process?

• To synthesize new DNA
• To chop off the mutant strand
• To identify mutations
• To stabilize the DNA structure

How does DNA polymerase contribute to the repair of a mutation after EXO1 has acted?

• It identifies the mutation
• It synthesizes the correct DNA strand
• It unwinds the DNA double helix
• It recruits other repair proteins