Wound Healing Quiz

What is the primary purpose of wound healing?

• To increase blood flow

• To reduce pain

• To prevent infection

• To promote inflammation

Which phase of wound healing occurs immediately after injury?

• Remodeling phase

• Inflammatory phase

• Maturation phase

• Proliferative phase

What type of healing occurs with clean, uninfected surgical incisions?

• Healing by first intention

• Healing by second intention

• Healing by tertiary intention

• Healing by granulation

Which cells are primarily involved in the formation of granulation tissue?

• Epithelial cells

• Neutrophils

• Fibroblasts

• Macrophages

What is the role of matrix metalloproteinases (MMPs) in wound healing?

• Stimulate angiogenesis

• Degrade collagen and ECM components

• Enhance inflammation

• Promote fibroblast migration

Which growth factor is known to stimulate keratinocyte proliferation?

• TGF-α

• VEGF

• EGF

• PDGF

What is a characteristic of hypertrophic scars?

• Have a disorganized collagen pattern

• Stay within the limits of the original wound

• Regress spontaneously

• Grow beyond the original wound

What is the main difference between healing by first and second intention?

• Depth of the wound

• Presence of infection

• Type of growth factors involved

• Amount of necrotic tissue

Which factor can impair wound healing by causing ischemia?

• Antibiotic administration

• Mechanical debridement

• Adequate nutrition

• Diabetes

What is the expected tensile strength of scar tissue compared to original tissue?

• 80%

• 30%

• 50%

• 100%