Mutations Review

What mutation has occurred here?

T-G-A-C-C-A

T-G-A-G-C-A

• Substitution

• Deletion

• Insertion

• Frameshift

Tags

NGSS.HS-LS3-2

Which of the following would result in a frameshift mutation?

• Insertions only

• Substitution only

• Deletion only

• Insertions and Deletions

Tags

NGSS.HS-LS3-2

A mutation is defined as:

• A change in the cell's structure

• Anything that changes in an embryo

• Any change in the physical features of a human

• A change in the DNA sequence

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

ATTTGAGCC- Original

ATTGAGCC - Mutated

The example above is an example of a

• Insertion- Frameshift

• Deletion- Substitution

• Deletion -Frameshift

• All of the above

Tags

NGSS.HS-LS3-2

Why are insertion and deletion (frameshift) mutations so harmful?

• They change all of the codons from the mutation on down the line, which changes the amino acid sequence

• They insert things that an organism doesn't need.

• They often delete things that organisms need.

• Insertion and deletions are not any more harmful than substitution mutations.

Tags

NGSS.HS-LS3-2

Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA

• no mutation
• substitution
• insertion
• deletion

Tags

NGSS.HS-LS3-2

What is a Gene?

• A segment of RNA that encodes for a protein
• A chromosome
• A segment of DNA that encodes for a protein
• Your genome

Tags

NGSS.HS-LS1-1

A change in a gene, group of genes or chromosome that results in a change in the proteins

• Replication

• Mutations

• Translation

• Transcription

Tags

NGSS.HS-LS3-2

One nucleotide base is changed so only one amino acid

is affected

• Substitution Mutation

• Point Mutation

• Translocation

• Inverse Mutation

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

A point mutation where one nucleotide base replaces an original nucleotide base

• Inversion Mutation

• Chromosomal Mutation

• Translocation

• Substitution Mutation

Tags

NGSS.HS-LS3-2