Lecture 5

Antibodies are the antigen-specific products of B cells and the production of antibody in response to infection is the contribution of B cells to adaptive immunity.

 Also called​ (a)  

– Y-shaped

– Glycoproteins

– Produced by plasma ​ (b)  

– Antigen binding site is called ​ (c)  

– Types: IgG, IgA, IgM, IgE, IgD 

​ (d)   (surface of B cell) or ​ (e)  

• immunoglobulins (Ig)
• B-cells
• paratope.
• Membrane-bound
• secreted
• Antigens
• T-cells
• Cytokines
• epitope
• excreted

Identify the antigen-binding sites

Identify the Disulfide bonds

Identify the Heavy chains

Identify the Light chain

Identify the Fc domain

Fragment (crystallization)

Identify the Fab domain

Fragment (antigen-binding)

Identify the Amino terminal end

Identify the Fab or paratope

Identify the Carboxyl Terminal end