Lecture 1: Intro to Aging

When is the final exam for KINE4704/5510?

• December 6th, 2024

• December 12th, 2024

• November 30th, 2024

• There is no final exam

What does senescence mean?

• gradual deterioration of functional characteristics (cellular or whole organism)

• The gradual weakening of the heart's ability to pump blood efficiently as the cardiac muscle fibers slowly lose elasticity over time.

• The progressive decline in the body's ability to regenerate skin cells, leading to the thinning and wrinkling of the skin as one ages.

• The slow deterioration of muscle strength and coordination due to the gradual loss of motor neurons in the aging nervous system.

What defines an older adult?

• ≥ 60 years of age

• ≥ 65 years of age

• 50 years of age

• 80+ years of age

In 2050, ____ of older people will be living in low- and middle-income countries.

Which province has the highest growth rate of of older adults 75+.

• Nunavut

• Ontario

• Nova Scotia

• British Columbia

Which province has the high proportion of older adults?

• New Brunswick

• PEI

• Nova Scotia

• Newfoundland

What is the definition of functional age?

• Perceived age based on physical function

• True age in years

• How old your cells are

• how effectively a person’s muscles can perform tasks

What is the definition of functional age?

• Perceived age based on physical function

• True age in years

• How old your cells are

• how effectively a person’s muscles can perform tasks

Which option is not a Primary Hallmark of aging?

• Telomere attrition

• Loss of proteostasis

• Cellular senescence

• Genomic instability

What is an example of Genomic Instability?

• A cell's DNA is exposed to excessive ultraviolet (UV) radiation and it can cause mutations.

• An imbalance in sleep patterns, which directly induces genetic mutations.

• Frequent changes in dietary preferences, leading to mutations in the cell's DNA.

• A cell is exposed to excessive amounts of water, causing its DNA to become unstable.