Week 5

How does acute inflammatory demyelinating polyneuropathy (AIDP) differ from acute motor axonal neuropathy (AMAN)?

• AMAN is more common in North America and is due to attack of the nodes of ranvier

• AIDP is more common in North America and is due to attack of the nodes of ranvier

• AMAN is more common in North America and is due to attack of the myelin sheaths

• AIDP is more common in North America and is due to attack of the myelin sheaths

What statement best characterizes amyotrophic lateral sclerosis?

• ALS is due to degeneration of the Betz cells in the primary somatosensory cortex and the cell bodies in the dorsal horn of the spinal cord

• ALS is due to degeneration of the Betz cells in the primary somatosensory cortex and the cell bodies in the anterior horn of the spinal cord

• ALS is due to degeneration of the Betz cells in the primary motor cortex and the cell bodies in the dorsal horn of the spinal cord

• ALS is due to degeneration of the Betz cells in the primary motor cortex and the cell bodies in the anterior horn of the spinal cord

Of the neurological conditions listed, which one does not seem to present with a genetic component to etiology?

• multiple sclerosis

• Guillain-Barre disease

• amyotrophic lateral sclerosis

• huntington’s disease

• parkinson’s disease

Which category of multiple sclerosis (MS) is characterized by distinct attacks or flares interrupted by recovery periods followed by periods of flares and progression between those attacks?

• clinically isolated syndrome

• relapsing-remitting MS

• primary progressive MS

• secondary progressive MS

Which condition is due to an acute demyelinating attack on the cranial nerves that results impaired ocular motion and overall motor incoordination?

• Amyotrophic lateral sclerosis

• Acute inflammatory demyelinating polyneuropathy

• miller fisher syndrome

• acute motor axonal neuropathy

Which type of spinal muscle atrophy is the most severe and common form?

• Type 1

• Type 2

• Type 3

• Type 4

Impairments to mood and behavior in individuals with either Parkinson’s or Huntington’s disease are likely due to the basal ganglia loops from which part of the cortex?

• motor cortex

• premotor cortex

• primary somatosensory cortex

• prefrontal cortex

What would post-mortem cross-sectional brain studies of individuals with huntington’s disease reveal?

• decreased size of the caudate, increased size of the lateral ventricles, and atrophy of the cortex without impairment to the cerebellum

• decreased size of the caudate, increased size of the lateral ventricles, and atrophy of the cerebral cortex and cerebellum.

• decreased size of the subthalamic nucleus and atrophy of the cerebral cortex and cerebellum

• decreased size of the subthalamic nucleus and atrophy of the cerebral cortex without impairment to the cerebellum

What terminology best describes this image?

• facial nerve palsy

• hypophonia

• hypomimia

• micrographia

In individuals with amyotrophic lateral sclerosis, which structures are spared from neurodegeneration?

• lateral corticospinal tract

• brainstem tracts for ocular motion

• rubrospinal tract

• motor and premotor cortices