Retake BioMEMs

Describe the whole process of the diagram, detailed as much as possible? (5 pt)

Why is photolithography not suitable for micropatterning proteins?

• 
  It cannot create precise patterns

• It is toxic to cells

• It inhibits the cleaning of cleanroom

• It causes denaturation of biomolecules

What is the advantage of physic-sorption over chemisorption?

• Forms stable chemical linkage

• Requires expertise of a chemist

• Requires specialized substrate

• Does not require surface treatment

In the Self-Assembled Monolayers (SAM), to minimum the free energy of the surface to form..........layer

What is the bonding between the PEG molecules and glass substrate?

To do SAM on a gold substrate, the functional group should be used is.....

• Thiol SH-

• Silane O-Si-O

• Amino NH2-

• None of them

Describe the process to obtain the Oligonucleotide Chips. As much as possible (5pt)

With electrophoresis, which kind of particles were NOT moved?

• Positive Particles

• Negative particles

• Neutral particles

What does Extracellular Matrix contain?

• Protein

• Nutrients

• Oxygen

• All of them

Which force forms when water associates with non-polar groups?

• Hydrogen bond

• 
  Electrostatic force

• Van der Waals force

• Hydrophobic force