Quiz 2

Characterized by development of (primitive)
erythroblasts that produce measurable amounts of
hemoglobin

• Mesoblastic Phase (Yolk Sac Phase)

• Hepatic Phase

• Medullary (Myeloid Phase)

Characterized by clusters of developing erythroblasts,
granulocytes, and monocytes

• Hepatic Phase

• Mesoblastic Phase (Yolk Sac Phase)

• Medullary (Myeloid Phase

Megakaryocytes begin being produced

• Hepatic Phase

• Medullary Phase (Myeloid)

• Mesoblastic Phase (Yolk Sac Phase)

Developing erythroblasts signal the beginning of
definitive

• hemotopoiesis

• hemostasis

• developing wbcs

Lymphoid cells begin to appear

• Hepatic

• Medullary (Myeloid)

• Mesoblastic Phase

Liver is major site and will retain activity until 1-2
wks after birth

• Hepatic Phase

• Mesoblastic Phase

• Medullary Phase

Contributes during the hepatic phase

• Spleen, kidney, thymus, and lymph nodes all will
  contribute during this phase

• Bone marrow, kidney, thymus, and lymph nodes all will
  contribute during this phase

• Spleen, kidney, thymus, and brain all will
  contribute during this phase

• Spleen, kidney, liver, and lymph nodes all will
  contribute during this phase

main site of production of TPO

• Liver

• Spleen

• Brain

• Kidneys

control the production and release
of platelets

• 
  TPO and IL11

• IL3 and IL11

• TPO

• GM-CSF, IL3, IL6, IL7, IL11, kit ligand, and
  TPO

MEGAKARYOPOIESIS

• GM-CSF, IL3, IL6, IL7, IL11, kit ligand, and
  TPO

• CFU-GEMM and IL3

• IL6,IL7,kit ligand