IMMUNOSERO PART 7 (21-25)

Forward light scatter in cell flow cytometry (March 2024 recall)

• measures complexity

• measures cell granularity

• measures cell size

• measures subpopulation of cells

Answer explanation

Side light scatter measures cell GRANULARITY or COMPLEXITY

E- rosette assay uses_ RBC as reagent for enumeration of T cells

• rabbit

• human

• hamster

• sheep

Answer explanation

Sheep RBC attaches to CD2+ of T cells

substances that stimulate cell division

• immunogens

• mitogens

• antigens

• antibodies

All antigens are immunogens

• True

• False

Answer explanation

All immunogens are antigens BUT not all antigens are immunogens

Factors influencing the immune response

• dose

• route of inoculation

• age

• Genetic

Most immunogenic

• protein

• carbohydrates

• lipids

• nucleic acid

Answer explanation

carbohydrates - 2nd most immunogenic, lipid & nucleic acid - least or non-immunogenic

Antigen from two different spp.

• autoantigens

• alloantigens

• heteroantigens

• heterophile antigens

consist of sequential amino acids on a single polypeptide chain

• confirmational epitopes

• Linear epitopes

• determinant site

Haptens are_

• immunogens

• adjuvant

• antigen

• NOTA

Answer explanation