Purines

What are the treatments for Lesch-Nyhan syndrome, and which is considered second-line therapy?

What mnemonic can be used to remember the symptoms of Lesch-Nyhan syndrome, and what does each letter stand for?

Which enzyme is responsible for converting guanine to GMP in the purine salvage pathway?

Answer explanation

Answer: HGPRT (hypoxanthine-guanine phosphoribosyltransferase) is the enzyme responsible for converting guanine to GMP in the purine salvage pathway.

What enzyme converts xanthine to uric acid, and what is the end product of this conversion?

Answer explanation

Answer: Xanthine oxidase is the enzyme that converts xanthine to uric acid, with uric acid being the end product of this conversion.

Which purine is characterized by an amino group at the 12 o'clock position?

Answer explanation

{{c1::Adenine}}

What are DNA and RNA made of, and what type of bond connects these components?

Answer explanation

Answer: DNA and RNA are made of nucleotide monophosphates connected via a phosphodiester bond.

How many hydrogen bonds exist between a G-C base pairing?

Answer explanation

Three

What amino acids are necessary for purine synthesis?

Answer explanation

{{c1::Glycine, Aspartate, Glutamine::3}}