Predictive Methods Using DNA Sequences -3

Predictive Methods Using DNA Sequences -3

Assessment

Passage

Biology

12th Grade

Hard

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8 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the accuracy of PROCRUSTES in predicting correct gene structures when using candidate proteins?

90%

75%

50%

99%

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the purpose of GenomeScan program?

To predict gene structures based on DNA sequence alone

To assign a higher score to putative exons that overlap BLASTX hits

To analyze nonstandard gene structures

To identify protein sequences in the public databases

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the main function of the Type column in the GENSCAN output table?

Provides the probability value of the prediction

Shows the direction of the prediction

Indicates the length of the prediction

Specifies the type of prediction (e.g., initial exon, internal exon)

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the accuracy of GENSCAN exons with a very high probability value (P > 0.99) when matching a true, annotated exon?

50%

75%

88.1%

97.7%

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the purpose of the GenomeScan program when a moderate or closely related protein sequence is available?

To improve the accuracy of gene structure prediction

To predict gene structures based on DNA sequence alone

To assign a lower score to putative exons

To ignore regions of high detected similarity

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What does the algorithm of PROCRUSTES require before making a prediction?

Public databases

DNA sequence with content-based signals

BLASTX hits

Candidate proteins

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the significance of the phrase 'he who stretches' in the context of Greek mythology?

Symbolizes the idea of forcing something to fit

Represents the accuracy of gene prediction

Describes the hero Theseus

Refers to a bandit with a warped idea of hospitality

8.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the main advantage of using candidate proteins in the PROCRUSTES algorithm?

Reduces the need for spliced alignment algorithm

Increases the number of predicted exons

Provides information about public databases

Improves the accuracy of gene structure prediction