CHEM 465 Lipid Catabolism Part 1 17.1 & 17.2a

What are some advantages of fats over polysaccharides?

• Fats carry more energy per carbon

• Fats carry less energy per carbon

• Fats carry less water along

• Fats carry more water along

​ (a)   are for stort-term energy needs/

• Glucose & Glycogen
• Protein & Fiber
• Lipids & Minerals
• Glucose & Glucagon
• Lipids & Glucagon

What is made up of a chylomicron?

• Cholesterol

• Triacylglycerols and cholesteryl esters

• Apolipoproteins

• Glucose

• Glycogen

The enzyme used to breakdown triglycerides

Triglycerides are broken down into by the enzyme

• Enzyme: Lipase

  Broken down into: Glycerol and Alkyl Chains

• Enzyme: Triase

  Broken down into: Ester and Fatty Acids

• Enzyme: Lipase

  Broken down into: Ester and Fatty Acids

• Enzyme: Triase

  Broken down into: Glycerol and Alkyl Chains

What type of reaction is the lipase reaction?

• Hydrolysis

• Substrate-Level Phosphorylation

• Esterification

• Condensation

What type of tissue is triacylglycerols stored in?

• Adipose tissue

• Skeletal tissue

• Liver tissue

• Stomach tissue

Reorder the following

• Hormone binds to receptor and stimulates adenylyl cyclase to produce cAMP

• PKA is activated by phosphorylation to activate the hormone-sensitive lipase molecule to access the lipid droplet

• Lipid droplet forms, hydrolyzing triacylglycerols to free fatty acids that leave the adipocyte and bind serum albumin in the blood

• The fatty acids are oxidized to CO2 and the energy of oxidation is conserved in ATP, which fuels muscle contraction and other energy-requiring metabolism in the myocyte

• Once carried into the blood, they are released from the albumin and enter a myocyte from a specific fatty acid transporter.

The molecules on the surface which phosphorylates with the hormone-sensitive lipase

What is the name of the molecule that fatty acids binds to in the blood?

(Hint: Think of egg whites)