Pre-Board Hematology Pt.1.2

Which of the following is contained in the primary granules of the neutrophil?

• lactoferrin

• myeloperoxidase

• histamine

• alkaline phosphatase

The morphological characteristic associated with Chediak-Higashi syndrome is:

• pale blue cytoplasmic inclusiosns

• giant lysosomal granules

• small, dark staining granules and condensed nuclei

• nuclear hyposegmentation

Auer rods may be seen in all of the following except:

• acute myelomonocytic leukemia (M4)

• acute lymphoblastic leukemia

• acute myeloid leukemia without maturation (M1)

• acute promyelocytic leukemia (M3)

Which type of anemia is usually present in a patient with acute leukemia?

• microcytic, hyperchromic

• microcytic, hypochromic

• normocytic, normochromic

• macrocytic, normochromic

In leukemia, which term describes a peripheral blood finding of leukocytosis with a shift to the left, accompanied by occasional nucleated red cells?

• megaloblastosis

• dysplasia

• leukoerythroblastosis

• none of these

DIC is most often associated with which of the following types of acute leukemia?

• acute myeloid leukemia without maturation

• acute promyelocytic leukemia

• acute myelomonocytic leukemia

• acute monocytic leukemia

A peripheral smear shows 75% blasts. These stain positive for both Sudan black B (SBB) and peroxidase (Px). Given these values, which of the following disorders is most likely?

• AML

• CML

• AUL

• ALL

Sodium fluoride may be added to the naphthyl ASD acetate (NASDA) esterase reaction. The fluoride is added to inhibit a positive reaction with:

• megakaryocytes

• monocytes

• erythrocytes

• granulocytes

In essential thrombocythemia, the platelets are:

• increased in number and functionally abnormal

• normal in number and functionally abnormal

• decreased number and functional

• decreased in number and functionally abnormal

Which of the following cells is considered pathognomonic for Hodgkin’s disease?

• Niemann-Pick cells

• reactive lymphocytes

• flame cells

• Reed-Sternberg cells