Neuromuscular Physiology

The neuromuscular junction (NMJ) is a ___, allowing communication to occur between a cell of the peripheral nervous system (neuron) and a cell/fiber of skeletal muscle.

• Synapse

• Connection

• Junction

• Transmitter

Where is the neuromuscular junction (NMJ) located?

• At the point where a motor neuron meets a muscle fiber
• In the digestive system
• Center of each muscle fiber and there is only one NMJ per fiber

• At the point where a motor neuron meets a bone

The Neuromuscular junction (NMJ) is also referred as...

• Motor end plate

• Synapse

• Neurotransmitter site

• Muscle receptor

Neuromuscular junction (NMJ) has 2 tissues which are separated by a small space called...

• Neural gap

• Muscle divide

• Synaptic cleft

• Synapse

The pre-synaptic (neural) side contains vesicles filled with the neurotransmitter...

• tranverse (T) tubules

• Acetylcholine (ACh)

• mitochondria
• Acetylcholine receptors (AChR)

ACh binds to ___ that are positioned on the post-synaptic membrane of the skeletal muscle...

• Acetylcholine receptors (AChR)

• Sarcomere

• Terminal cisternae

• Tranverse (T) tubules

The AChRs open as ligand-gated channels to allow ___ to enter the muscle cell...

• Chloride (Cl-)

• Calcium (Ca2+)

• Sodium (Na+)

• Potassium (K+)

Action potential within the fiber (AChRs) also known as...

• Muscle action potential (MAP)

• Tropomyosin

• Sarcoplasmic reticulum

• Tranverse (T) tubules

The MAP travels down the plasma membrane into the...

• Terminal cisternae

• Acetylcholine receptors (AChR)

• Tranverse (T) tubules

• Sarcomere

A calcium ion reservoir...

• Tropomyosin

• Acetylcholine receptors (AChR)

• Muscle action potential (MAP)

• Sarcoplasmic reticulum