CHEM 465 Glycogenolysis and Glycogenesis

What three enzymes are Glycogenolysis?

• Glycogen Phosphorylase

• Glycogen Debranching Enzyme

• Phospho-glucomutase

• UDG-Glucose Pyrophoylase

• Glycogen Synthase

What three enzymes are Glycogenesis?

• Glycogen Phosphorylase

• Amylo to Transglycosylase

• Phospho-glucomutase

• UDG-Glucose Pyrophoylase

• Glycogen Synthase

Where Glycogenolysis occurs

Where is glycogen mainly stored?

• Liver Tissue

• Skeletal Muscles

• Bone Tissue

• Gut Tissue

The first enzyme in Glycogenolysis

Where does the glucose go after ___ enzyme occurs?

• Enzyme: Glycogen phosphorylase

  Goes to Glycolysis

• Enzyme: UDG-Glucose Pyrophosphorylase

  Goes to Gluconeogenesis

• Enzyme: UDG-Glucose Pyrophosphorylase

  Goes to Glycolysis

• Enzyme: Glycogen phosphorylase

  Goes to Glucoenogenesis

• Enzyme: Glycogen Synthase

  Goes to the next step in glycogenolysis

This element measures the Glucose in Glycogenolysis by oxidizind the glucose molecule

• Copper

• Magnesium

• Zinc

• Phosphorus

Glycogen Phosphorylase contains ____ for P_i Transfer

What is true?

i. The Oxidizing of glucose molecule is the Reducing End

ii. The PLP Attacks the Reducing End of the Glycogen molecule

• i. only

• ii. only

• both i. and ii.

• neither i. and ii.

Answer explanation

The oxidized end of glucose is the reducing end.

The reducing end of glucose is where the glycogen is branched and therefore, it is difficult for PLP to attack these oxidized part of glucose

PLP attacks the ___ ends of Glycogen.

Also indicate if the end is the oxidized or reduced form of glucose

• Non reducing ends of glucose

  The Glucose is reduced

• The non reducing ends of glucose The glucose is oxidized

• The reducing ends of glucose

  The glucose is reduced

• The reducing ends of glucose

  The glucose is oxidized