Coagulation Cascade

What is the primary function of secondary hemostasis?

• Restoration of blood flow

• Dissolution of the clot

• Formation of platelet plug

• Prevention of blood loss

Which factor is responsible for stabilizing fibrin into stronger fibers?

• Factor 8

• Factor 9

• Factor 13

• Factor 10

What is the main purpose of the coagulation cascade?

• To form platelet plug

• To trap red blood cells

• To dissolve the clot

• To stop bleeding efficiently

Which pathway of the coagulation cascade is faster but less efficient?

• Intrinsic pathway

• Extrinsic pathway

• Both pathways are equally efficient

• None of the above

What is the evidence that triggers the extrinsic pathway of the coagulation cascade?

• Activated factor 8

• Activated factor 9

• Activated factor 12

• Exposed subendothelial collagen

Which factor is activated by the tissue factor in the extrinsic pathway?

• Factor 7

• Factor 8

• Factor 9

• Factor 10

What activates factor 10 into 10a in the intrinsic pathway?

• Factor 8

• Subendothelial collagen

• Factor 9

• Von Willebrand factor

What is the function of the prothrombinase complex in the coagulation cascade?

• To stabilize fibrin fibers

• To activate factor 7

• To convert prothrombin to thrombin

• To trap red blood cells

What is the role of von Willebrand factor in the intrinsic pathway?

• Activates factor 10

• Activates factor 9

• Activates factor 8

• Activates factor 7

What is the main difference between the intrinsic and extrinsic pathways?

• Number of factors involved

• Speed of activation

• Efficiency in stopping bleeding

• Activation by tissue factor