AP Biology Cell Cycle

What is the role of cyclins in the regulation of the cell cycle?

• Cyclins are only involved in DNA replication and not in cell division

• Cyclins bind to and activate cyclin-dependent kinases (CDKs) to regulate the cell cycle.

• Cyclins inhibit the activity of cyclin-dependent kinases (CDKs) in the cell cycle

• Cyclins have no role in the regulation of the cell cycle

Explain the function of cyclin-dependent kinases (CDKs) in the cell cycle.

• CDKs inhibit the progression of the cell cycle by dephosphorylating target proteins.

• CDKs have no role in regulating the cell cycle.

• CDKs promote the cell cycle by preventing the phosphorylation of target proteins.

• CDKs regulate the progression of the cell cycle by phosphorylating target proteins.

Tags

NGSS.HS-LS1-4

What are the main cell cycle checkpoints?

• G1 checkpoint, G2 checkpoint, M checkpoint

• G0 checkpoint, G3 checkpoint, S checkpoint

• M checkpoint, G1 checkpoint, G3 checkpoint

• S checkpoint, G3 checkpoint, N checkpoint

How do cells respond to DNA damage at the G1 checkpoint?

• Shutting down repair mechanisms

• Increasing cell metabolism

• Activating repair mechanisms or initiating apoptosis

• Halting cell division

Describe the role of tumor suppressor genes in preventing cancer.

• Tumor suppressor genes promote uncontrolled cell growth and division

• Tumor suppressor genes have no role in preventing cancer

• Tumor suppressor genes promote cancer development

• Tumor suppressor genes prevent uncontrolled cell growth and division, and promote cell death if necessary.

What are the key differences between normal cell division and cancer cell division?

• Color of the cells

• Size of the cells

• Shape of the cells

• Regulation of cell growth, ability to stop dividing, potential for uncontrolled growth and spread

What is metastasis in relation to cancer and the cell cycle?

• Metastasis is the spread of cancer cells from the original tumor to other parts of the body.

• Metastasis is the process of cancer cells staying localized in the original tumor

• Metastasis is the result of the cell cycle stopping in cancer cells

• Metastasis is the movement of healthy cells to the site of a cancerous tumor

How do mutations in genes involved in the cell cycle contribute to the development of cancer?

• Uncontrolled cell division

• Enhanced cell repair mechanisms

• Decreased cell division

• Increased cell differentiation

Tags

NGSS.HS-LS1-4

NGSS.HS-LS3-2

Which are potential strategies for targeting the cell cycle in cancer treatment?

• Increasing cyclin-dependent kinases activity

• Inhibiting the DNA damage response pathway

• Promoting the formation of a healthy mitotic spindle

• Inhibiting cyclin-dependent kinases, targeting the DNA damage response pathway, and disrupting the mitotic spindle

Tags

NGSS.HS-LS1-4