Overview of DPN and Gabapentin - Quiz 2

How does exercise primarily induce glucose utilization in patients with Type 2 diabetes?

• By increasing insulin production from the pancreas

• By reducing insulin sensitivity in muscle cells

• By activating glucose transporters on muscle cell membranes

• By decreasing the body's ability to metabolize carbohydrates

How did researchers track the experience of pain among subjects in the gabapentin study?

• Quizzes

• Urinalysis

• Muscle biopsies

• Diaries

Why is subjective pain assessment considered challenging in research studies focusing on diabetic peripheral neuropathy?

• Due to the lack of standardized pain measurement tools

• Because diabetic neuropathy pain is not affected by subjective experiences

• Objective tests can evaluate neuropathic pain accurately

• Subjective pain reports are always consistent across different individuals

What technique was used to measure GLUT4 content from muscle biopsies taken in the exercise study discussed?

• Immunoblotting

• Immunohistochemistry

• Peripheral blood smear

• Immunofluorescence

How many weeks were the gabapentin and placebo groups on a fixed dose?

• 2 weeks

• 4 weeks

• 7 weeks

• 8 weeks

The polyol pathway produces the excess by-products, sorbitol, and fructose. Which best describes what this excess does to myo-inositol?

• Increase expression, uptake, and concentration of myo-inositol

• Increase only the concentration of myo-inositol

• Decrease expression, uptake, and concentration of myo-inositol

• Decrease only the concentration of myo-inositol

True or False: AGEs that are deposited in and around the tissues within the body are able to be removed simply by exercising.

• True

• False

Select all that apply: Which of the following are complications that can arise from diabetes mellitus?

• Amputation

• Kidney Disease

• Alzheimer's Disease

• Heart Disease

What symptom of DPN leads to the feelings of swollen feet and cold legs?

• Pain

• Allodynia

• Unusual Sensations

• Paresthesia

Overall, which of the following describes the most effective prevention, management, and treatment options for DPN?

• Regular exercise, glycemic control, and pharmaceuticals for pain

• Regular exercise, B12, and balance practice

• Balanced diet, genetics, and resistance training to prevent atrophy

• Lifestyle modifications, sleeping more, and pharmaceuticals for pain