Explanations of Schizophrenia

Which neurotransmitter was first linked to schizophrenia (Sz)?

• dopamine
• norepinephrine
• acetylcholine
• serotonin

In which part of the brain were excess levels of Da found?

• occipital lobe

• Frontal lobe
• mesocortical pathway

• mesolimbic pathway

A deficit of Da is linked to negative symptoms of Sz such as....

• hallucinations

• speech poverty

• delusions

• disorganised thinking

What is the name of the researcher who challenges the Da hypothesis?

• Cooper et al

• Bob

• Rosenhan

• Carlsson

Which of the following is a gene linked to Sz?

• CAN gene

• CANT gene

• COMT gene

• CAMP gene

How is this gene linked to Sz?

• If it's too strong, it cases excess levels of Da

• It's deletion means that Da levels are poorly regulated

• If too weak, it results in a deficit of Da

• It causes hallucinations

Why is deletion of the COMT gene linked to poor regulation of Da?

• It provides instructions for creation of the enzyme which breaks down Da

• It is linked to Parkinson's disease

• It provides instructions for creating GABA

• It' linked to the brain

Which other condition is linked to people who have Sz

• Di Graham syndrome

• Di Williams disease

• Di David syndrome

• Di George syndrome

A further gene linked to Sz is.....

• Gene X

• DISC1

• DISC2

• DISCO

The DISC1 gene codes for the creation of which neurotransmitter?

• Dopamine

• adrenaline

• BABA

• GABA