Endocrine Pharm Quiz

Which of the following pharmacologic agents, used in the management of T2DM, has an adverse effect of pancreatitis and should be avoided in patients with chronic pancreatitis?

• sulfonylurea

• GLP-1 receptor agonist

• metformin

• SGLT2 inhibitor

Which of the following is an insulin secretegogue?

• metformin

• glyburide

• canagliflozin

• sitagliptin

Which of the following is LEAST likely to cause hypoglycemia as monotherapy?

• metformin

• glyburide

• insulin

• None of these agents cause hypoglycemia

GLP-1 receptor agonists should NOT be used in combination with:

• GLP-1 receptor agonist can be safely combined with any of these agents

• SGLT2 inhibitor

• metformin

• DPP-4 inhibitor

Weight gain is an associated adverse effect of all of the following EXCEPT:

• insulin

• sulfonylurea

• GLP-1 receptor agonist

• None of these agents cause weight gain

Can sulfonylureas be used effectively throughout the entire course of T2DM (15 years and beyond)?

• Yes - they are very effective medications!

• No- due to B cell "burnout"

• Yes - these are effective medications for both Type I and Type II diabetes treatment

• No - due to the proliferation and regeneration of B cells that occurs later in the disease process

Which insulin has the longest duration of action?

• insulin aspart

• regular insulin

• NPH insulin

• insulin glargine

Where do the SGLT2 inhibitors exert their mechanism of action?

• B cells of the pancreas

• hepatocyte

• proximal convoluted tubule

• distal convoluted tubule

All of the following are effects of corticosteroids EXCEPT:

• increased risk of infection

• decreased inflammation

• delayed wound healing

• decreased blood glucose

Aldosterone deficiency results in:

• hypertension

• hypotension

• decreased serum potassium levels

• increased serum sodium levels

Tags

NGSS.HS-LS1-3