B cell activation

__________ mediates the process of Somatic hypermutation and Class switch recombination.

People with mutations in AID gene may overproduce _________ class of antibodies.

• IgG

• IgM

• IgA

• IgD

Plasma cells of the _________ produce class switched and high affinity antibodies.

• follicles

• germinal center

• primary focus

• all of the above

________ B cells have limited diversity and are found mainly in the pleural and peritoneal cavities.

Marginal zone B cells have the following characteristics:

• Recirculating, moderate V region diversity

• Reside in spleen, high V region diversity

• Reside in spleen, moderate V region diversity

• Recirculating, high V region diversity

________ are a source of natural IgM antibodies.

_________ and _______ are TI-1 and TI-2 antigens respectively.

• LPS, Flagellin

• Flagellin, LPS

• Sheep RBC, LPS

• Sheep RBC, Flagellin

_________ is an activated B cell that divides rapidly but secretes low levels of antibody.