p53 and the Cell Cycle Quiz

What is the role of p53 in apoptosis?

• p53 inhibits genes involved in apoptosis.

• p53 activates genes involved in apoptosis

• p53 has no role in apoptosis.

• p53 regulates cell division.

Which subtopic of p53 is related to cell cycle checkpoints?

• Apoptosis regulation

• DNA repair mechanisms

• Regulation of the Cell Cycle

• Transcriptional activation

What happens when p53 detects DNA damage during the cell cycle?

• It promotes cell division.

• It inhibits DNA repair mechanisms.

• It has no effect on the cell cycle.

• It activates DNA repair mechanisms or triggers apoptosis.

How does p53 regulate the cell cycle?

• p53 regulates the cell cycle by halting it at the G1 phase and initiating DNA repair or apoptosis.

• p53 regulates the cell cycle by inhibiting DNA repair or apoptosis.

• p53 regulates the cell cycle by accelerating it at the G1 phase.

• p53 regulates the cell cycle by promoting cell division at every phase.

What is the function of p53 in preventing cancer?

• p53 inhibits DNA repair and promotes cancer development.

• p53 regulates the cell cycle, promotes DNA repair, and induces apoptosis to prevent cancer.

• p53 promotes cell division and tumor growth.

• p53 has no role in preventing cancer.

What are the consequences of p53 mutation in the cell cycle?

• Impaired cell division, disrupted DNA damage repair, and decreased risk of cancer development.

• The consequences of p53 mutation in the cell cycle include impaired DNA damage repair, disrupted cell cycle checkpoints, and increased risk of cancer development.

• Enhanced cell cycle checkpoints, improved DNA damage repair, and decreased risk of cancer development.

• Increased cell division, reduced DNA damage repair, and decreased risk of cancer development.

How does p53 induce apoptosis?

• By blocking the release of cytochrome c from mitochondria.

• By promoting cell division and inhibiting cell death.

• By activating pro-apoptotic genes and suppressing anti-apoptotic genes.

• By inhibiting pro-apoptotic genes and activating anti-apoptotic genes.

What are the key cell cycle checkpoints regulated by p53?

• S/G2 checkpoint and M/G1 checkpoint

• G1 checkpoint and M checkpoint

• G2 checkpoint and S checkpoint

• G1/S checkpoint and G2/M checkpoint

What happens when p53 is absent or non-functional in the cell cycle?

• Uncontrolled cell division and increased risk of cancer

• Decreased cell growth

• Normal cell division

• Decreased risk of cancer