442.2023 ABO &Lewis

How many ABO genotypes are there?

• 3

• 4

• 5

• 6

Which ABO blood group is the most common in Kuwait?

• A

• B

• O

• AB

If an individual carries the genotype Hh. Which antigen(s) could he express?

• H antigen

• h antigen

• H antigen + h antigen

Which of the following precursor structures can result in a soluble A antigen?

• Type 1 chain h antigen

• Type 2 chain h antigen

• Type 1 chain H antigen

• Type 2 chain H antigen

Which sugar is transferred by α-2-L-fucosyltransferase?

• GalNac

• Galactose

• Sugar α-2

• Fucose

What does the B gene code for?

• B antigen

• A antigen

• Gal transferase

• Does not code for anything

Which of the following influences the expression of membrane-bound A antigen in an individual with the A gene?

• Se gene

• H gene

• h gene

• Type 1 chain availability

If the mother is: AO, Father is: AO
What is the likelihood of their offspring having blood group A?

• 25%

• 50%

• 75%

• 100%

A request came in for a newborn ABO group. What is your interpretation of the following results:

• Baby is group O

• Baby is group AB

• Reverse grouping discrepancy. Must repeat the test

Why are transfusion reactions associated with Lewis antibodies rare?

• Because Lewis antigens are not expressed early in life

• Because Lewis antibodies do not exist

• Because Lewis antibodies are IgM cold reacting

• Because Lewis antibodies are IgG