CC LEC EXAM - AST, ALT

E.C. nomenclature for Aspartate Aminotransferase

Old name for AST

• serum glutamic-oxaloacetic transaminase (SGOT)

• L-Alanine: 2- Oxoglutarate Aminotransferase

• serum glutamic-pyruvic transaminase (SGPT)

• L-Aspartate: 2-Oxoglutarate Aminotransferase

coenzyme used by AST

• Pyridoxal phosphate

• nicotineamide

• FAD

• NADP

Highest concentration of AST is found in

• Cardiac Tissue

• Liver

• Skeletal Muscle

• Kidney

• Pancreas

Intracellular AST concentration is ____ higher than extracellular concentration

Isoenzymes of AST mainly from RBC and Heart and predominant form occurring in serum

• Cell Cytoplasm

• Mitochondria

Isoenzymes of AST mainly present in the liver. Increases in disorders producing cellular necrosis

• Cell Cytoplasm

• Mitochondria

AST in AMI begins to rise within

• 6-8 hours

• 2-4 hours

• 1-2 hours

• 3-4 hours

AST is a specific test for AMI

• False

• True

Half-life of ALT and AST according to Bishop

• ALT 24h, AST 16h

• ALT 48h, AST 18h

• ALT 24h, AST 17h

• ALT 47h, AST 17h