MCQ from Molecular basis of inheritance by Shailja Dubey(kV

Who proposed the Central Dogma?

• Francis Crick

• Frederick Griffith

• Meselson and Stahl

• James Watson

Name the stage in the cell cycle where DNA replication occurs .

• G1-phase

• M-phase

• S-phase

• G2-phase

What role does the enzyme DNA ligase play during DNA replication

• Joins nucleotides

• Cleaves nucleotides

• Opens the helix

• Maintains the helix

The switching 'on' and 'off ' of the lac operon in prokaryotes is regulated by

• Glucose

• Galactose

• Lactose

• Fructose

Which of the following steps in transcription is catalysed by RNA polymerase?

• Initiation

• Elongation

• Termination

• All of the above

The net electric charge on DNA and histones is

• Both positive

• Both negative

• Negative and positive, respectively

• Zero

In some viruses ,DNA is synthesised by using RNA as template .Such a DNA is called

• A-DNA

• B-DNA

• cDNA

• rDNA

Discountinuous synthesis of DNA occurs in one strand , because

• DNA molecule being synthesised is very long

• DNA dependent DNA polymerase catalysed polymerisation only in one direction (5'-3' )

• It is a more efficient process

• DNA ligase joins the short stretches of DNA

Control of gene expression in prokaryotes take place at the level of

• DNA-replication

• Transcription

• Translation

• None of the above

Which was the last human chromosome to be completely sequenced

• Chromosome 1

• Chromosome 11

• Chromosome 21

• Chromosome X