Quiz about Biochem FINAL: Replication/transcription/translation

Question 1

Mitosis must be regulated.

Accepted Answer

True

Answer

False

Question 2

Nucleosomes disassembled as replication begins and proteins form

Accepted Answer

S phase

Answer

M phase

Answer

G phase

Question 3

Breakdown of nuclear membrane, spindle fibers appear, chromosomes condense

Accepted Answer

Prophase

Answer

Metaphase

Answer

Anaphase

Answer

Telophase

Question 4

Spindle fibers attach to chromosomes and chromosomes condense

Accepted Answer

Prometaphase

Answer

Prophase

Answer

Metaphase

Answer

Anaphase

Question 5

Centromeres divide and sister chromatids move to opposite sides of the cell

Accepted Answer

Anaphase

Answer

Prophase

Answer

Metaphase

Answer

Telophase

Question 6

When does the spindle fiber dissapear?

Accepted Answer

Telophase

Answer

Prophase

Answer

Metaphase

Answer

Anaphase

Question 7

Colchicine (Colcrys) keeps spindle fibers from forming

Accepted Answer

True

Answer

False

Question 8

Spindle fibers are also known as

Accepted Answer

microtubules

Answer

not this

Question 9

Packed nucleosomes condensed during mitosis

Accepted Answer

chromosome

Answer

nucleosome

Answer

ds helix

Question 10

ds helix wrapped around an octamer of histones

Accepted Answer

nucleosome

Answer

chromatin

Answer

ds DNA chain

Question 11

ds helix wraps up around histone

Accepted Answer

chromatin

Answer

nucleosome

Question 12

coiling of ds chain

Accepted Answer

ds helix

Answer

dsDNA chain

Answer

nucleosome

Question 13

2 complete chaines H-bonded in antiparallel orientation

Accepted Answer

dsDNA chain

Answer

ds helix

Answer

nucleosome

Question 14

polymers of nucleotides

Accepted Answer

oligonucleotide

Answer

nucleoside

Question 15

nucleoside + 3 phosphates

Accepted Answer

nucleotide

Answer

nucleoside

Question 16

base + sugar

Accepted Answer

nucleoside

Answer

nucleotide

Question 17

Deoxyribose is a ___ carbon sugar molecule

Accepted Answer

5

Answer

6

Answer

8

Question 18

Where does phosphate group of DNA attach?

Accepted Answer

C5

Answer

C7

Answer

C3

Question 19

Adenine and Guanine

Accepted Answer

purines

Answer

pyrimidines

Question 20

Thymine and Cytosine

Accepted Answer

pyrimidines

Answer

purines

Question 21

Ribose-5-phosphate is formed in

Accepted Answer

PPP

Answer

glycolysis

Answer

citric acid cycle

Question 22

which one?

Accepted Answer

Ribose

Answer

Deoxyribose

Question 23

Which one?

Accepted Answer

Deoxyribose

Answer

Ribose

Question 24

Which ones are 2 ring structures?

Accepted Answer

Purines

Answer

Pyrimidines

Question 25

Which ones are one ring structures?

Accepted Answer

Pyrimidines

Answer

Purines

Question 26

What is the only difference in thymine and uracil?

Accepted Answer

the methyl group

Answer

not this

Question 27

Select the features of nitrogenous bases.

Accepted Answer

planar to allow for pi pi stacking

Accepted Answer

good H-bond acceptors and donors

Accepted Answer

neutral at pH of 7

Accepted Answer

C and N atoms ont eh base numbered cyclically

Question 28

DNA is neutral at pH of 7.

Accepted Answer

False

Answer

True

Question 29

beta-glycosidic linkages link the pentose sugar and the

Accepted Answer

nitrogenous base

Answer

phosphate

Question 30

B-glycosidic linkages form on C1 of sugar and ____ in purines.

Accepted Answer

N9

Answer

N1

Question 31

B-glycosidic linkages form between C1 of sugar and ___ of pyrimidines.

Accepted Answer

N1

Answer

N9

Question 32

All sugars are oriented in the same direction on both DNA strands.

Accepted Answer

True

Answer

False

Question 33

2 ester bonds being formed using phosphoric acid

Accepted Answer

phosphodiester linkage

Answer

B-glycosidic linkage

Question 34

phosphodiester linkages repeat in the ___ direction

Accepted Answer

5' --> 3'

Answer

3' --> 5'

Question 35

Adenine with Thymine

Accepted Answer

2 H bonds

Answer

3 H bonds

Question 36

Cytosine with Guanine

Accepted Answer

3 H bonds

Answer

2 H bonds

Question 37

Which part of DNA is exposed to the solvent?

Accepted Answer

sugar/phosphate backbone

Answer

nitrogenous bases

Question 38

Which part of DNA is NOT exposed to the solvent?

Accepted Answer

nitrogenous bases

Answer

sugar/phosphate backbone

Question 39

hydrophobic part of DNA

Accepted Answer

nitrogenous bases

Answer

sugar/phosphate backbone

Question 40

After every ___ basepairs there is a twist.

Accepted Answer

10

Answer

5

Question 41

base pairs in the core of the helix have e's that interact with one another to generate

Accepted Answer

hydrophobic stacking

Answer

hydrophilic stacking

Question 42

pi-pi stacking stabilizes the helix.

Accepted Answer

True

Answer

False

Question 43

site of DNA replication in prokaryotes

Accepted Answer

cytosol

Answer

nucleus

Question 44

How many sites of origin to prokaryotes have?

Accepted Answer

1

Answer

many

Question 45

how many sites of origin are in eukaryotes?

Accepted Answer

many

Answer

1

Question 46

For each origin, there are 2 replication forks.

Accepted Answer

True

Answer

False

Question 47

DNA has a "bubble appearance" at the replication forks

Accepted Answer

True

Answer

False

Question 48

Prokaryotes have ___ DNA than eukaryotes

Accepted Answer

less

Answer

more

Question 49

unwinds DNA

Accepted Answer

helicase

Answer

lipase

Answer

topoisomerase

Question 50

Prevent the two unwound DNA strands from coming back together during replication

Accepted Answer

single-stranded binding proteins (SSBs)

Answer

topoisomerase

Answer

helicase

Question 51

Cuts both strands and helps with the strain that is placed on the DNA helix.

Accepted Answer

topoisomerase II

Answer

helicase

Answer

SSBs

Question 52

Topoisomerase requires energy and prevents supercoiling.

Accepted Answer

True

Answer

False

Question 53

Topoisomerase I cuts

Accepted Answer

1 strand

Answer

2 strands

Question 54

Topoisomerase II cuts

Accepted Answer

2 strands

Answer

1 strand

Question 55

Enzyme that adds nucleotides to growing DNA strand

Accepted Answer

DNA polymerase

Answer

topoisomerse

Answer

helicase

Question 56

DNA polymerase needs an RNA primer before it can start.

Accepted Answer

True

Answer

False

Question 57

RNA primers added by primase during DNA replication get replaced with DNA later in the process

Accepted Answer

True

Answer

False

Question 58

ATP, UTP, GTP and CTP are

Accepted Answer

RNA triphosphates

Answer

DNA triphosphates

Question 59

dTTP, dATP, dGTP, and dCTP are

Accepted Answer

DNA triphosphates for primase

Answer

RNA triphosphates for primase

Question 60

Mg is cofactor for DNA polymerase

Accepted Answer

True

Answer

False

Question 61

made discontinuoulsy away from the replication fork

Accepted Answer

lagging strand

Answer

leading strand

Question 62

made continuously as replication fork advances

Accepted Answer

leading strand

Answer

lagging strand

Question 63

joins Okazaki fragments together

Accepted Answer

ligase

Answer

primase

Question 64

Where are errors more likely due to Okazaki fragments?

Accepted Answer

lagging strand

Answer

leading strand

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