Class XI - Complex Traits

Complex traits typically involve contributions from

• Genes

• Environment

• Genes + Environment

Traits involving the contribution of multiple genes are:

• polygon

• polygenic

• polyploid

• polymath

The amount of a trait due to genetic variation is referred to as:

• Gene x environment

• GWAS

• Heritability

• Hemizygosity

Tags

NGSS.HS-LS3-2

NGSS.HS-LS3-3

A SNP was identified in a GWAS study that is statistically associated with height. This SNP directly contributes to height variation in humans

• True

• False

Tags

NGSS.HS-LS3-2

Plot type used to visualize GWAS studies

• Manhatten

• Houston

• Scatter

• Skyline

You assess association of 100 SNPs with a trait of interest. At a p-value cutoff of 0.05, how many of your significant SNPs are false positive?

• 5

• 10

• 0

• 1

Tags

NGSS.HS-LS4-3

Clustering of significant SNPs in a GWAS study is due to which phenomenon?

• Linkage

• Crossing over

• Chance

• Copy number variation

Plants with different genotypes sometimes respond differently to the same environmental cue (e.g., soil nutrients, sunlight, etc.). This is:

• gene by environment interactions

• epistasis

• codominance

• reversion

Tags

NGSS.HS-LS3-1

NGSS.HS-LS4-5