Flavivirus

Flavivirus is a non-envelope virus

• True

• False

Flavivirus is a negative sense, single-stranded RNA virus

• True

• False

Which of the following statements is TRUE about flavivirus genome?

• 5’ end with methylated nucleotide cap and 3’ terminus lacks of poly-A tail.

• Five structural proteins (capsid, E3, E2, 6K, E1)

• Four non-structural proteins (nsP1, nsp2, nsp3, nsp4) 

• Two open reading frame (ORF) encode for non-structural protein and structural protein

Symptoms of Japanese encephalitis include fever, headache, vomiting, and seizures 

• True

• False

There are 3 lineages of Zika virus; African, Asian and European.

• True

• False

Culex mosquito is the vector of Japanese encephalitis virus.

• True

• False

There are no specific vaccines or treatments for dengue and Zika virus infection.

• True

• False

In Baltimore classification, flavivirus is classified as 

• Group III

• Group I

• Group VI

• Group IV

Which of the following is the most common method of transmission for Flavivirus?

• Inhalation of contaminated air

• Ingestion of contaminated food or water

• Direct contact with an infected person's blood or bodily flui

• Bites from infected mosquitoes

Which of the following symptoms are commonly associated with Flavivirus?

• Fever, joint pain, and rash

• Chest pain, shortness of breath, and coughing

• Diarrhea

• Worts and blisters