ERT320- Quiz 1

Define what is Bioseparation Engineering...

• an unsystematic study of the scientific and engineering principles utilized for the large-scale purification of biological products.

• a pilot study of the scientific and engineering principles utilized for the large-scale purification of biological products.

• a systematic study of the scientific and engineering principles utilized for the large-scale purification of biological products.

• an engineering principles utilized for the large-scale purification of biological products.

Bioprocessing can be broadly classified into 2 categories. Name 2 of the categories.

• Radioactive and Extractive bioprocessing

• Reactive and Extractive bioprocessing

• Reactive and passive bioprocessing

• Reactive and non-reactive bioprocessing

Identify whether the flow chart is reactive or extractive bioprocessing.

• Reactive Bioprocessing

• Extractive Bioprocessing

Economic importance of bioseparation: What is normally be the limiting factor in the commercialization of a biological product?

• in the purification process, the product is technically difficult and cheap.

• in the drying process, the starting material e.g. cell culture media is technically difficult and expensive.

• in the purification process, the starting material e.g. cell culture media is technically difficult and expensive.

• in the collection process, the starting material e.g. cell culture media is technically difficult and expensive.

Bioseparation is largely based on chemical separation processes. TRUE or FALSE

• TRUE

• FALSE

Fill in the blank:

________products are present in very low concentrations in the starting material from which they are purified.

• Chemical

• Biological

• Physical

• Natural

Fill in the blank:

__________therapeutic products should be free from impurities.

• Injectable

• Projectable

• Edible

• Natural

Biological products are separated based on one or more of the following factors: EXCEPT

• Size: e.g. filtration, membrane separation, centrifugation

• Density: e.g. centrifugation, sedimentation, floatation

• Solubility: e.g. extraction, precipitation, crystallization

• Chemical name: e.g. ethanol, hexane, butanol

Particle-liquid separation is one of the physical forms separated in bioseparation. TRUE or FALSE?

• TRUE

• FALSE

Separation of dissolved antibiotics from cells and cell debris present in the fermentation broth can be separated using particle-solute separation in liquid medium. TRUE or FALSE?

• TRUE

• FALSE