UNIT 1

Physicochemical properties in relation to biological actions includes

• Solubility

• Ionization

• Sterochemistrt

• All of the above

Factors Affecting Partition Coefficient

• pH

• Co solvent

• none of the above

• Both

100% of Drug is taken, where if 95% of drug binds

then what about the rest of the drug which is still present in the body, and in which form?

• 5%

  Active

• 5%

  Inactive

Optical Isomers - clockwise

• dextro

• laevo

• + & -

• +

In Geometric Isomerism

Based on position of the functional group the isomers are named as:

• Trans

  &

  Cis

• Dextro

  &

  Laevo

• Both

• none