Which of the following drugs may be associated with bradycardia? Select ALL that apply.

Quiz Bowl Training 1

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Other
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University
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Hard
Jessica Vu
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40 questions
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1.
MULTIPLE SELECT QUESTION
30 sec • 1 pt
amlodipine
bisoprolol
clonidine
enalapril
ivabradine
Answer explanation
Bisoprolol, clonidine, and ivabradine can cause bradycardia and/or heart block. Non-DHP CCBs also decrease AV nodal conduction and can cause bradycardia. DHP CCBs like amlodipine have no effect on AV nodal conduction, instead they can cause reflex tachycardia. ACEis like enalapril have no effect on cardiac conduction.
2.
MULTIPLE CHOICE QUESTION
20 sec • 1 pt
Which of the following drugs antagonize both B1 and B2 receptors at low doses?
atenolol
bisoprolol
carvedilol
metoprolol
nebivolol
Answer explanation
Carvedilol is a nonselective B-blocker, antagonizing both the B1 and B2 receptors. The remaining choices are cardioselective, especially at low doses. Metoprolol also becomes non-selective at about 100 mg/day
3.
MULTIPLE SELECT QUESTION
30 sec • 1 pt
Which of the following drugs have been shown to improve survival in patients with heart failure with reduced ejection fraction (HFrEF)? Select ALL that apply.
carvedilol
digoxin
enalapril
ivabradine
spironolactone
Answer explanation
Ivabradine has been associated with a reduction in hospitalizations in patients with HFrEF but not with a reduction in mortality. Digoxin can reduce symptoms in HFrEF patients but has not been associated with a reduction in mortality.
4.
MULTIPLE SELECT QUESTION
30 sec • 1 pt
Which of the following oral antithrombotic agents is/are approved for the treatment of deep venous thrombosis (DVT) and pulmonary embolism (PE)?
apixaban
aspirin
dabigatran
rivaroxaban
ticagrelor
Answer explanation
Antiplatelet medications like aspirin or ticagrelor would not be useful for treating DVT or PE.
5.
MULTIPLE CHOICE QUESTION
20 sec • 1 pt
Thiazide diuretics should NOT be used as a first line treatment for hypertension in patient suffering from:
hyperlipidemia
heart failure
gout
COPD
Answer explanation
Thiazide diuretics may increase the reabsorption of uric acid from renal tubules and may cause hyperuricemia. It should NOT be used as a first line treatment for hypertension in patients suffering from gout.
6.
MULTIPLE CHOICE QUESTION
20 sec • 1 pt
Which of the following is considered first-line therapy for reducing the risk of atherosclerotic cardiovascular disease (ASCVD)?
HMG Co-A reductase inhibitors
bile acid resins
nicotinic acid
fibrates
Answer explanation
ATP4 found that the use of statins for prevention of ASCVD is extensive and consistent. Statin therapy is recommended for patients at a higher risk of ASCVD who are most likely to experience a net benefit in terms of the potential for risk reduction vs the potential for adverse effects. Non-statin therapies do not provide sufficient benefits in the reduction of ASCVD risk in regards to their potential for adverse effects.
7.
MULTIPLE SELECT QUESTION
45 sec • 1 pt
DB is a 63-year-old male who is coming into your clinic today to discuss his Coumadin therapy. He currently takes 5 mg M-F and 7.5mg on Sat/Sun for his chronic non-valvular atrial fibrillation. Recently he has noticed increased bleeding of his gums and has experienced a couple of nosebleeds which is unusual for him. His INR today is 4.6. Which of the following could be possible explanations for an increased INR while on Coumadin? Select all that apply.
Increased dietary intake of leafy green vegetables
Initiation of Bactrim
Binge alcohol use
Uncontrolled hyperthyroidism
Missed doses
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