NMR Metabolomics

Metabolomics involves the study of...?

• mRNA

• Genes

• Metabolites

• Protein

Answer explanation

Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample.

Which of the following classes of molecules could be defined as small molecules?

• Amino acids

• tRNA

• Polypeptides

• Polymers

The specific effects of a therapeutic on the arginine pathway can be studied using a...

• Untargeted metabolomics

• Targeted metabolomics

Sample preparation involves the following steps

• Extraction

• Interpretation

• Data processing

Nuclear magnetic resonance spectroscopy is more reproducible than mass spectrometry

• True

• False

The minimum number of biological replicates is

• 1

• 2

• 3

• 4

The minimum number of technical replicates is

• 1

• 2

• 3

• 4

Below are the QC samples in NMR metabolomics EXCEPT

• Biological Replicates

• Technical Replicates

• Internal Standard

• Blank Solvent

NMR Data processing involves

• Baseline Correction

• Correlation Analysis

• Annotation

• Multivariate Analysis

NMR Software use for data pre-processing is

• MZMine

• Chenomx

• SIMCA

• MSDial