Huntington's, Alzheimer's, and other neurological disorders

What disease is a fatal, genetic disorder that causes the progressive breakdown of nerve cells in the brain?

• MS

• alzheimer's

• huntington's

• ALS

What does Huntington’s Disease cause?

• involuntary movements

• behavioral changes

• cognitive decline

• fasciculations

TRUE/FALSE: males are more affected by Huntington’s disease than females.

• TRUE

• FALSE

Answer explanation

both sexes are equally affected

What is the onset of Huntington’s Disease typically?

• between 65-75 years old

• upon birth

• between 30-50 years old

• after menopause in women

The Huntingtin protein is expressed in higher/lower concentrations in the brain.

• higher

• lower

TRUE/FALSE: Huntington's disease is an inherited disorder

• true

• false

Huntington’s Disease is characterized by:

• abnormally choreoathetosis movements of limbs

• rhythmic movements of the tongue and face

• mental deterioration (leading to psychosis and dementia)

• rapid progressive weakness

Which disorder results from neurotransmitter imbalance in which GABA functions are diminished and dopaminergic functions are enhanced in the striatum

• huntington's

• alzheimer's

• MS

• ALS

What is the only drug approved for the treatment of chorea in Huntington’s Disease?

• riluzole

• tetrabenzine

• fingolimod

• exelon

What is the class of tetrabenazine?

• dopamine-related drug (monoamine depletion)

• glutamate receptor antagonist

• central acetylcholinesterase inhibitors

• interferon beta-1a agonist