Molecular basis of inheritance

Who amongst the following scientist had no contribution in the development of the double helix model for the structure of DNA?

• Rosalind Franklin

• Maurice Wilkins

• Erwin Chargaff

• Meselson and Stahl

If a double stranded DNA has 20% of cytosine, what will be the percentage of adenine in it?

• 20%

• 40%

• 30%

• 60%

If the sequence of bases in one strand of DNA is ATGCATGCA what would be the sequence of bases on complementary strand?

• ATGCATGCA

• AUGCAUGCA

• TACTACGT

• UACGUACGU

Which of the following phenomena was experimentally proved by Meselson and Stahl?

• Transformation

• Transduction

• Semi conversative DNA replication

• Central dogma

First experimental proof for semi conservative DNA replication was shown in

• Streptococcus pneumoniae

• Escherichia coli

• Neurospora chrasa

• Rattus rattus

Which non radioactive isotope was used by Meselson and Stahl in their experiments?

• ³² P

• ³⁵ S

• ¹⁵ N

• None

Based on the experiments by Hershey and Chase, which of the following statements are true? (Choose all the correct answers)

• (i) They conducted their experiment on the fact that DNA contains phosphorous.

• (ii) They conducted their experiments on the fact that proteins contain phosphorous.

• (iii) They incorporated radioactive isotope of phosphorous into bacteriophage.

• (iv) They showed that when P32 was used all radioactivity was associated with bacterial cells

• (v) The isotopes P32 and S35 were used independantly to infect the bacterium E coli

Which one of the following condition can cause pneumonia in mice?

• Injection of R strain into mice.

• Injection of heat killed R strain into mice along with heat killed S strain.

• Injection of heat killed S strain into mice.

• Injection of live S strain into mice or heat killed S strain along with live R strain.

Who discovered the process of transformation and on which species was it done?

• Frederich Miescher, Streptococcus pneumoniae

• Frederick Griffith, Streptococcus pneumoniae

• Alfred Hershey, T2 Bacteriophage

• Martha Chase, T2 bacteriophage

The isotopes used by Hershey and Chase to prove that DNA is the genetic material R

• P32 and S35

• P35 and S32

• N15 and N15

• N14 and N15