Molecular basis of inheritance -8

Translation occurs in

• nucleus

• cytoplasm

• nucleolus

• lysosome

During translation, proteins are synthesised

• by ribosomes using the information from DNA

• by lysosomes using the information from DNA

• by ribosomes using the information from mRNA

• by ribosomes using the information from rRNA

The enzyme involved in amino acid activation is

• ATP synthase

• aminoacyl tRNA synthetase

• aminoacyl mRNA synthetase

• aminoacyl rRNA synthetase

Which of the following RNA molecules serves as an adaptor molecule during proteins synthesis

• rRNA

• mRNA

• tRNA

• tRNA and mRNA

In prokaryotes, the first amino acid in the polypeptide chain is

• methionine

• N-methyl methionine

• N-formyl methionine

• All of these

During translation, the role of enzyme peptidyl transferase is

• transfer of phosphate group

• amino acid activation

• peptide bond formation between adjacent amino acids

• binding of ribsosome subunits to mRNA

Polysomes are

• Aggregation of ribosomes

• aggregation of lysosomes

• mRNA molecules to which many ribosomes are attached simultaneously

• all of these

Which is the energy rich molecule required for initiation of translation

• ATP

• GTP

• CTP

• AMP

eRF1 is the release factor in eukaryotes that requires

• ATP for its binding to ribosome

• GTP for its binding to ribosomes

• ATP and GTP for its binding to ribosome

• Mn for its binding to ribosomes

The ribosome has three binding sites (A, P, E) for tRNA molecules. Which of the following is NOT the correct statement regarding these sites?

• The A site binds to an incoming aminoacyl-tRNA

• The P site codon is occupied by peptidyl-tRNA (an amino acid containing tRNA)

• The E site is occupied by empty t-RNA as it is exiting the ribosome

• None of the Above