Enzyme Chemistry (Part 3)

In an enzymatic reaction, the concentration of ____________ decreases while the concentration of products increases.

When substrate concentration is in excess/too high, ______

• there will be steep increase in rate of enzymatic reaction

• reaction rate is following 1st order kinetics

• there will be saturation of enzyme-substrate complexes

• the apoenzyme dislodges from the holoenzyme

Concentration of enzymes is directly proportional with enzyme activity under the condition that _________

• there is insufficient substrate

• there is excess amounts of substrates

• the enzyme belongs to the classification of hydrolases

All enzymes work at an optimum pH of about 8.

• True

• False

When inhibition is irreversible, it means

• the enzyme inhibitor form non-covalent interactions with enzyme

• the enzyme inhibitor form ionic interactions with the enzyme

• the enzyme inhibitor form covalent bonds with the enzyme

• the enzyme has denatured