Haemoglobin & Dissociation Curves

How many polypeptide chains does Haemoglobin (Hb) consist of?

• One

• Two

• Three

• Four

Where in the Hb molecule do molecules of oxygen bind?

• To the haem group

• To amino acids in the polypeptide chains

• In the cytoplasm of the erythrocyte

• In the plasma

Which ion does Haemoglobin (Hb) contain in the haem group?

• Chloride

• Iron (Fe2+)

• Iron (Fe3+)

• Protons

Which of the following is not a means by which carbon dioxide is carried in the blood?

• Dissolved in the plasma as CO2

• Dissolved in the plasma as HCO3-

• Dissolved in the cytoplasm of the erythrocyte as HCO3-

• Bound to Hb directly

What is formed when CO2 reacts with water (H20) in the blood plasma?

• Carbonic anhydrase

• Haemoglobinic acid

• Carbonic acid

• None of the above

What is formed when CO2 reacts with water (H20) in the cytoplasm of an erythrocyte?

• Carbonic anhydrase

• Haemoglobinic acid

• Carbonic acid (H2CO3)

• None of the above

What is the name of the enzyme that catalyses the reaction between CO2 and water (H20) in the cytoplasm of an erythrocyte?

• Carbonic anhydrase

• Haemoglobinic acid

• Carbonic acid (H2CO3)

• None of the above

When CO2 binds directly to Hb, what does it form?

• Carbonic anhydrase

• Haemoglobinic acid

• Carbonic acid (H2CO3)

• None of the above

Once H2CO3 (carbonic acid) has formed, what does it dissociate into?

• Hb + protons

• protons + HCO3-

• HCO3- + CO2

• HHb

Where do the HCO3- ions move to once dissociated from H2CO3?

• Cytoplasm

• Tissue fluid

• Plasma

• Hb