LA Fill in the blanks

Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to _Q1______ions and ___ ions are actively extruded from the cell in exchange for ___________ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens __________ channels, allowing a rapid inward current of __________ions to flow increasing the potential to + 40mV. These channels then become inactive. ___________ channels then open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Sodium

• Potassium

•Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and ___Q2__ ions are actively extruded from the cell in exchange for ___________ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens __________ channels, allowing a rapid inward current of __________ions to flow increasing the potential to + 40mV. These channels then become inactive. ___________ channels then open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Potassium

• Sodium

•Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and Na+ ions are actively extruded from the cell in exchange for _Q3_ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens __________ channels, allowing a rapid inward current of __________ions to flow increasing the potential to + 40mV. These channels then become inactive. ___________ channels the open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Potassium

• Sodium

•Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and Na+ ions are actively extruded from the cell in exchange for K+ ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens _Q4 channels, allowing a rapid inward current of __________ions to flow increasing the potential to + 40mV. These channels then become inactive. ___________ channels the open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Sodium

• Potassium

Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and Na+ ions are actively extruded from the cell in exchange for K+ ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens Na+ channels, allowing a rapid inward current of ______Q5____ions to flow increasing the potential to + 40mV. These channels then become inactive. ___________ channels then open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Sodium

• Potassium

Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and Na+ ions are actively extruded from the cell in exchange for K+ ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens sodium channels, allowing a rapid inward current of _Na+ __ions to flow increasing the potential to + 40mV. These channels then become inactive. _Q6__________ channels then open and the outward flow of _________ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Sodium

• Potassium

Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and Na+ ions are actively extruded from the cell in exchange for K+ ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens Na+ channels, allowing a rapid inward current of _Na+ ions to flow increasing the potential to + 40mV. These channels then become inactive. Potassium channels then open and the outward flow of __Q7_______ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _______channels to the resting state.

• Sodium

• Potassium

Under resting conditions, neurons maintain a negative internal potential between about -60 to -80 mV. This arises because the membrane is relatively impermeable to Na+ ions and _K+ ions are actively extruded from the cell in exchange for Na+ ions by an energy-dependent transporter Na+/K+ ATPase pump. During the physiological initiation or propagation of a nerve impulse, the first event is a small depolarisation of the membrane, produced either by transmitter action or by the approach of an action potential passing along the axon. This opens Na+ channels, allowing a rapid inward current of _Na+ ions to flow increasing the potential to + 40mV. These channels then become inactive. Potassium channels then open and the outward flow of __K+ ions allow the membrane to repolarize to -95mV. This repolarization facilitates the return of _____Q8__channels to the resting state.

• Sodium

• Potassium