Clot Resolution & Anticoagulation

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Clot Resolution & Anticoagulation

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Antithrombin III and Protein C/S prevent overclotting.

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Disorders of Coagulation

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Thromboembolic: excessive clotting

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Thromboembolic Disorders

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Disorders involving blood clots that can travel and block blood vessels.

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Causes of Thromboembolic Disorders

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Atherosclerosis, infection, trauma, genetics

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Risks associated with Thromboembolic Disorders

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Slow flow, viscous blood

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Examples of Thromboembolic Disorders

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DVT, embolism, Factor V Leiden

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DVT complications

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Can travel to lungs, brain, or heart and cause embolisms, affecting PVD.

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Hemophilia

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Missing clotting factors

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Liver disease

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Decreased factor synthesis

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Thrombocytopenia

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Low platelets