Pharmacology

Front

Phenylephrine

Back

- Mechanism: A1 selective - Indications: Decongestant, hypotension - Adverse Effects: Rebound congestion, reflex bradycardia - Nursing Considerations: Monitor for hypertension, short-term use only

Front

Clonidine

Back

- Mechanism: A2 selective - Indications: Hypertension, ADHD, opioid withdrawal - Adverse Effects: Sedation, dry mouth, severe rebound hypertension, constipation - Nursing Considerations: Taper dose, patch rotation site weekly

Front

Dobutamine

Back

- Mechanism: B1 selective - Indications: Acute heart failure, cardiogenic shock - Adverse Effects: Tachycardia, arrhythmias, angina, hypotension - Nursing Considerations: Monitor ECG, BP, urine output, dosing IV infusion only

Front

Albuterol, Salmeterol

Back

- Mechanism: B2 selective - Indications: Asthma, COPD rescue - Adverse Effects: Tremor, tachycardia, hypokalemia - Nursing Considerations: Teach correct inhaler use, overuse can cause bronchospasm

Front

Terbutaline

Back

- Mechanism: B2 selective - Indications: Asthma, COPD rescue, preterm labor - Adverse Effects: Tremor, tachycardia, hyperglycemia - Nursing Considerations: Monitor HR and blood glucose, short-term for OB, overuse can cause bronchospasm

Front

Dopamine

Back

- Mechanism: Nonselective A/B (dose-dependent: A1 and B1) - Indications: Shock, heart failure, renal perfusion - Adverse Effects: Tachycardia, dysrhythmias, extravasation - Nursing Considerations: Monitor vitals, urine output, IV site

Front

Epinephrine

Back

- Mechanism: Nonselective A/B - Indications: Anaphylaxis, cardiac arrest, asthma - Adverse Effects: Tachycardia, hypertension - Nursing Considerations: Monitor HR and airway, teach injection technique

Front

Norepinephrine

Back

Nonselective A/B (A1, A2, B1) used for septic shock. Causes hypertension, reflex bradycardia, extravasation, ischemia. Monitor BP and HR, administer through central line only. Antidote is Phentolamine.

Front

Doxazosin

Back

Selective A1 Blocker for hypertension and benign prostatic hyperplasia. Can cause first-dose syncope and dizziness. Administer at bedtime, monitor BP, educate fall risk.

Front

Phentolamine

Back

Nonselective A1 and A2 blockers for pheochromocytoma and as an antidote for epi/norepi extravasation. Causes reflex tachycardia, hypotension, nasal congestion. Injections at extravasation site, monitor HR and BP, fall risk due to hypotension.