Hemolytic Anemias

Front

These inclusions which cannot be visualized on Wright-stained peripheral smears are often associated with:

Back

G6PD deficiency

Front

Which RBC morphology is formed as a result of Heinz bodies being pitted from the RBC in the spleen? Options: acanthocytes, burr cells, stomatocytes

Back

bite cells

Front

Which hemolytic disorder has RBCs that are especially sensitive to lysis by complement? Options: PNH, PCH, Hereditary spherocytosis, G6PD deficiency

Back

PNH

Front

An anemia that manifests as decreased marrow cellularity, cytopenias in two cellular elements, and reticulocytopenia is termed

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Aplastic anemia

Front

Individuals with Fanconi's anemia characteristically show

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Increased Hgb F

Front

Which of the following red cell indices would most likely be found in Hereditary spherocytosis? MCV - 87, MCH - 29.9, MCHC- 34.5; MCV - 65, MCH - 27, MCHC - 29.8; MCV - 80.5, MCH - 33.4, MCHC - 39.0; MCV 101, MCH 30, MCHC - 33.0

Back

MCV - 80.5, MCH - 33.4, MCHC - 39.0

Front

Choose the principal confirmation test for a diagnosis of hereditary spherocytosis: autohemolysis test, sucrose hemolysis test, thermal stability test, osmotic fragility test

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osmotic fragility test

Front

Which erythrocyte disorder is associated with abnormal membrane permeability? Options: hereditary elliptocytosis, hereditary stomatocytosis, PNH, hereditary spherocytosis

Back

hereditary stomatocytosis

Front

The osmotic fragility test determines whether a patient's RBCs are osmotically fragile by measuring the amount of hemolysis that occurs when a patients RBCs have been incubated in various concentrations of hypotonic saline.

Back

when a patients RBCs have been incubated in various concentrations of hypotonic saline

Front

Immunophenotyping for a diagnosis of PNH uses the following monoclonal antibodies?

Back

CD55 and CD59